Sara Russo

48 Chapter 2 CONFLICT OF INTEREST The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. AUTHORS CONTRIBUTION SR, MK, NG, RB, and BM conceived and designed the set-up of the manuscript. SR drafted the manuscript and prepared figures. SR, MK, NG, RB, and BM edited and revised the manuscript and all approved the final version. FUNDING This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 754425. ACKNOWLEDGMENTS The Figures 1,2,3,4,5 were created with BioRender.com.

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