64 Chapter 3.1 Table 3: Mixed effect modelling to estimate the magnitude of the change in ISQ according to visit and abutment size. Statistically significant results are in bold. ISQ_LOW ISQ_HIGH Mean Change (95% CI) p value Mean Change (95% CI) p value 6 mm Post op visit week 1 -8.5 (-13.4, 3.6) 0.001 -8.2 (-13.0, -3.5) 0.001 Post op visit week 2 2.2 (-3.3, 7.6) 0.44 0.3 (-5.0, 5.6) 0.92 3 months 3.2 (-1.8, 8.2) 0.21 3.5 (-1.3, 8.4) 0.16 6 months -1.4 (-13.1, 10.4) 0.82 -1.4 (-12.9, 10.1) 0.82 9 months 6.3 (1.2, 11.4) 0.015 3.2 (-1.8, 8.1) 0.21 12 months 5.2 (0.1, 10.3) 0.045 2.5 (-2.4, 7.5) 0.32 9 mm Post op visit week 1 1.1 (-1.6, 3.8) 0.43 2.4 (-0.4, 5.2) 0.1 Post op visit week 2 -0.3 (-3.5, 2.9) 0.86 1.0 (-2.5, 4.4) 0.58 3 months 7.7 (4.8, 10.5) <0.0001 9.8 (6.8, 12.8) <0.0001 6 months 8.0 (4.0, 12.0) <0.0001 10.1 (5.8, 14.3) <0.0001 9 months 9.7 (6.1, 13.2) <0.0001 9.4 (5.7, 13.1) <0.0001 12 months 10.1 (6.6, 13.4) <0.0001 9.5 (5.8, 13.1) <0.0001 12 mm Post op visit week 1 1.2 (-3.8, 6.2) 0.63 9.5 (-0.4, 19.4) 0.06 Post op visit week 2 -3.4 (-8.9, 2.1) 0.23 4.1 (-6.6, 14.8) 0.45 3 months -3.0 (-8.0, 1.9) 0.23 4.0 (-5.9, 13.9) 0.43 6 months 8.3 (0.1, 16.6) 0.048 21.8 (6.1, 37.4) 0.006 9 months -8.5 (-16.7, -0.3) 0.042 -3.3 (-18.9, 12.4) 0.68 12 months -3.9 (-10.0, 2.2) 0.21 10.8 (-1.4, 22.9) 0.08 All abutments Post op visit week 1 -0.21 (-2,55, 2,14) 0.86 1.05 (-1.42, 3.52) 0.40 Post op visit week 2 0.04 (-2.75, 2.83) 0.98 0.66 (-2.72, 3.60) 0.66 3 months 6.51 (4.03, 8.99) <0.0001 8.42 (5.80, 11.04) <0.0001 6 months 6.85 (3.20, 10.49) <0.0001 8.66 (4.82, 12.50) <0.0001 9 months 8.82 (5.83, 11.82) <0.0001 8.20 (5.08, 11.32) <0.0001 12 months 9.03 (6.12, 11.95) <0.0001 8.43 (5.36, 11.50) <0.0001
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