Chapter 4 112 predictors. All analyses including the CAR were tested in an unadjusted model (the marginal model) and an adjusted model including age, current smoking, and work vs day off status of saliva sampling, as covariates (the covariate-controlled model). Since there was a difference in sleep quality in the OC users compared to the NC women, we tested whether the CAR mediated the group differences in PSQI scores. We conducted a mediation analysis by assessing the overall group difference between OC users and NC women (i.e. the c-path), the group difference in CAR (i.e. the a-path), the association between the CAR and the PSQI score (i.e. the b-path), as well as the group difference between OC users and NC women after controlling for the CAR (i.e. the c’-path) using linear regression analyses. For the analyses comparing OC and NC group (i.e., the mediation analysis of the CAR and PSQI sum score and the covariate-controlled moderation analysis of CAR and PSQI 5B), we adjusted the p-values, resulting in adjustment for four repeated tests. 3. Results 3.1. Demographic characteristics and clinical profiles The demographic and clinical characteristics of the study sample are displayed in Table 4.1. The NC women, OC users and men show no differences in age, parity, education score, BMI, MDI and PSS score. Men were significantly older than NC women (mean age: 25.2 and 24.4, respectively), and fewer men (52%) than NC women and OC users (77% and 78%, respectively) reported being single.
RkJQdWJsaXNoZXIy MTk4NDMw