Associations between sex hormones, sleep problems and depression 243 Administration, 2018). As mentioned, the antidepressant fluoxetine is intermittently prescribed against depressive symptoms in PMDD. In 2019 a specific antidepressant for postpartum depression, brexanolone (Zulresso), an analogue of a progesterone metabolite, was fast-track approved by the FDA (Canady, 2019; Food and Drug Administration, 2019). These developments already indicate a growth in research on sex-specific knowledge and treatment options in sleep problems and depression, and future research should further clarify the effects of sex hormones as well.
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