Table of contents Chapter 1 General Introduction 9 Chapter 2 Oral contraceptives, depressive and insomnia symptoms 41 in adult women with and without depression Chapter 3 Changes in depression symptom profile with gender- 69 affirming hormone use in transgender persons Chapter 4 Cortisol dynamics and sleep quality: the role of sex and 103 oral contraceptive use Chapter 5 Sex hormones, insomnia, and sleep quality: subjective sleep 133 in the first year of hormone use in transgender persons Chapter 6 Influence of sex hormone use on sleep architecture in 165 a transgender cohort: findings from the prospective RESTED study Chapter 7 Chronotype changes after sex hormone use: a prospective 195 cohort study in transgender users of gender- affirming hormones Chapter 8 Associations between sex hormones, sleep problems and 215 depression: a systematic review Chapter 9 General discussion 255 Appendix 295 English summary 297 Nederlandse samenvatting 305 Author contribution statement 313 Publications 317 Portfolio 319 Dankwoord 323 About the author 329
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