Chapter 3 96 Table S3.1. Results from analyses assessing changes in IDS-SR scores and subscale scores after 3 and 12 months of GAHT. Time point n IDS-SR total IDS-SR mood subscale IDS-SR anxiety subscale IDS-SR lethargy subscale IDS-SR somatic subscale Estimated difference in TF participants with complete GAHT Baseline 53 Reference Reference Reference Reference Reference 3 months 52 14.0% (-2.0% to 32.7%) p=0.097 2.6% (-12.2% to 20.0%) p=0.75 -6.3% (-20.3% to 10.1%) p=0.43 4.7% (-14.5% to 28.0%) p=0.66 12.5% (-3.4% to 31.0%) p=0.14 12 months 30 17.7% (-2.0% to 41.0%) p=0.088 26.3% (5.0% to 52.4%) p=0.016 -5.6% (-22.1% to 14.4%) p=0.56 9.0% (-14.5% to 38.2%) p=0.48 4.1% (-13.2% to 24.7%) p=0.67 Estimated difference in TF participants with incomplete GAHT Baseline 3 Reference Reference Reference Reference Reference 3 months 3 -8.9% (-51.6%; 71.5%) p=0.78 -20.6% (-58.7% to 52.6%) p=0.50 -29.1% (-63.9% to 39.4%) p=0.33 3.6% (-55.4% to 140.8%) p=0.94 -30.7% (-63.3% to 31.1%) p=0.27 12 months 1 -25.8% (-71.1%; 88.1%) p=0.54 -23.1% (-70.4% to 98.6%) p=0.60 11.2% (-66.7% to 137.7%) p=0.82 -54.8% (-86.7% to 53.1%) p=0.21 -55.8% (-82.5% to -11.5%) p=0.092
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