General Introduction and Thesis Outline | 17 Figure 3. RV deformation patterns Using deformation imaging and computer simulation, 3 distinctive characteristic RV longitudinal deformation patterns were identified by researchers from our institute in 2016.12 (Left) Type I normal deformation as seen in healthy controls. (Middle) Type II, characterized by delayed onset of shortening, reduced systolic peak strain, and minor post-systolic shortening. This pattern was reproduced by the computer simulation of severely reduced contractility and mildly increased passive stiffness in the basal (subtricuspid) RV segment. (Right) Type III, characterized by little or no systolic peak strain, predominantly systolic stretching, and major post-systolic shortening. This pattern was reproduced by introducing severely reduced contractility and severely increased passive stiffness in the basal segment. ECG = electrocardiogram; PVO/PVC = pulmonary valve opening/closure. (Copyright 2016 by Elsevier; reprinted with permission) 1
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