Left sided Wall Stress Causing Arrhythmia | 217 SUPPLEMENTAL MATERIAL Table S1. Variants of uncertain significance found in patients with MAD/MVP Patient Mutation Gene IVF survivor 3 VUS TMEM43 c.428C>T p.(Thr143Met) VUS DSP c.3230C>A p.(Ala1077Glu) IVF survivor 4 VUS TTN c.76352dupC Pro25452fs Table S2. Morphologic PVC criteria in patients with MAD/MVP Patient VE BBB pattern Precordial transition Axis Estimated origin IVF survivor 1 No N/A N/A N/A N/A IVF survivor 2 Yes RBBB V4 Superior LV inferoseptal LBBB V5 Inferior RVOT IVF survivor 3 No N/A N/A N/A N/A IVF survivor 4 Yes LBBB V3 Inferior RVOT (distal) IVF survivor 5 Yes RBBB Positive conc. Intermediair/ superior LV mid posterior IVF survivor 6 Yes LBBB V4 Inferior RVOT (distal) IVF survivor 7 Yes RBBB V5 Superior LV apex IVF survivor 8 Yes LBBB V4 Inferior RVOT distal lateral DD LVOT RCC 10
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