Right Ventricular Functional Abnormalities in ARVC | 51 Supplementary table 2. Clinical characteristics comparison of patients without and with history of life-threatening arrhythmia at inclusion, separated by center. (continued) All (n=160) (n=80) (n=80) No VA (n=113) (n=55) (n=58) VA (n=47) (n=25) (n=22) p-value PKP2, n(%) (n = 159) Oslo (n = 79) Utrecht (n = 80) 124 (78) 53 (67) 71 (89) 94 (84) 43 (80) 51 (88) 30 (64) 10 (40) 20 (91) 0.005 <0.001 0.71 ICD, n(%) (n = 148) Oslo (n = 80) Utrecht (n = 68) 20 (14) 7 (9) 13 (19) 2 (2) 0 (0) 2 (4) 18 (44) 7 (28) 11 (69) <0.001 <0.001 <0.001 Syncope, n(%) (n = 160) Oslo (n = 80) Utrecht (n = 80) 40 (25) 30 (38) 10 (13) 23 (20) 18 (33) 5 (9) 17 (36) 12 (48) 5 (23) 0.04 0.19 0.09 Values are, n (%), mean ± standard deviation. Abbreviations: AA med. = anti arrhythmic medication, BB = beta blockers, AC = arrhythmogenic cardiomyopathy, BSA = body surface area, ICD = implantable cardioverterdefibrillator, PKP2 = plakophillin-2, VA = life-threatening ventricular arrhythmia Supplementary table 3. Electrocardiographic parameter comparison between patients without and with history of life-threatening arrhythmia at inclusion, separated by center. All (n=160) (n=80) (n=80) No VA (n=113) (n=55) (n=58) VA (n=47) (n=25) (n=22) p-value HR, bpm (n = 158) Oslo (n = 78) Utrecht (n = 80) 60.6 ± 12.3 60.0 ± 11.9 61.1 ± 12.6 62.6 ± 12.7 62.4 ± 11.6 62.8 ± 13.7 55.8 ± 9.6 55.0 ± 11.0 56.8 ± 7.9 <0.001 0.009 0.02 TWI major, n(%) (n = 160) Oslo (n = 80) Utrecht (n = 80) 45 (28) 22 (28) 23 (29) 22 (20) 10 (18) 12 (21) 23 (49) 12 (48) 11 (50) <0.001 0.006 0.01 TWI minor, n(%) (n = 159) Oslo (n = 80) Utrecht (n = 79) 17 (11) 9 (11) 8 (10) 12 (11) 6 (11) 6 (11) 5 (11) 3 (12) 2 (9) 0.99 0.89 0.85 Ɛ wave, n(%) (n = 159) Oslo (n = 80) Utrecht (n = 79) 13 (8) 4 (5) 9 (11) 5 (5) 1 (2) 4 (7) 8 (17) 3 (12) 5 (23) 0.008 0.06 0.05* TAD>55ms, n(%) (n = 148) Oslo (n = 80) Utrecht (n = 68) 37 (25) 7 (9) 30 (44) 22 (21) 3 (6) 19 (37) 15 (37) 4 (16) 11 (69) 0.04 0.12 0.02 NSVT, n(%) (n = 80)# Oslo (n = 80) Utrecht (n = 0) 24 (30) 14 (26) 10 (40) 0.19 3
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