Electromechanical Substrate Characterization in ARVC | 75 SUPPLEMENTARY MATERIAL Supplemental Table 1. Parameter description Model parameter Description Location Monte Carlo PSO SfAct Lv (kPa) Linear scaling factor for active stress LV (90,150) (0,300) SfAct Sv (kPa) IVS (90,150) (0,300) SfAct RvApex (kPa) RVfw apex (30,150) (0,300) SfACt RvMid (kPa) RVfw mid (30,150) (0,300) SfAct RvBase (kPa) RVfw base (30,150) (0,300) k1 Lv (-) Non-linear scaling factor for passive stress LV (5,15) (1,100) k1 Sv (-) IVS (5,15) (1,100) k1 RvApex (-) RVfw apex (5,20) (1,100) K1 RvMid (-) RVfw mid (5,20) (1,100) k1 RvBase (-) RVfw base (5,20) (1,100) dT Lv (ms) Activation delay of segment relative to estimated AV-delay LV (-25,25) (-150,150) dT Sv (ms) IVS (-25,25) (-150,150) dT RvApex (ms) RVfw apex (-25,50) (-150,150) dT RvMid (ms) RVfw mid (-25,50) (-150,150) dT RvBase (ms) RVfw base (-25,50) (-150,150) AmRef Lv (cm2) Segment area at sarcomere length LVfw (0.8,1.2)*98 (0.5,2)*98 AmRef Sv (cm2) IVS (0.8,1.2)*49 (0.5,2)*49 AmRef Rv (cm2) RVfw (0.8,1.2)*129 (0.5,2)*129 TimeFac (-) Scaling factor for myocardial twitch duration (0.8,1.2) (0.1,2) Ls =2μm 4
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