210 | Appendix 4. Publications continued. Year Katarina Ochodnicka-Mackovicova, Mahnoush Bahjat, Timon A Bloedjes, Chiel Maas, Alexander M de Bruin, Richard J Bende, Carel J M van Noesel, Jeroen E J Guikema. NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity. Blood, 2015 Sep 10;126(11):1324-35. 2015 Katarina Ochodnicka-Mackovicova, Mahnoush Bahjat, Chiel Maas, Amélie van der Veen, Timon A Bloedjes, Alexander M de Bruin, Harmen van Andel, Carol E Schrader, Rudi W Hendriks, Els Verhoeyen, Richard J Bende, Carel J M van Noesel, Jeroen E J Guikema. The DNA Damage Response Regulates RAG1/2 Expression in Pre-B Cells through ATM-FOXO1 Signaling. J Immunol, 2016 Oct 1;197(7):2918-29 2016 Katarina Hadova , Jana Kmecova, Katarina Ochodnicka-Mackovicova, Eva Kralova, Gabriel Doka, Lenka Bies Pivackova, Peter Vavrinec, Tatiana Stankovicova, Peter Krenek, Jan Klimas. Rapid changes of mRNA expressions of cardiac ion channels affected by Torsadogenic drugs influence susceptibility of rat hearts to arrhythmias induced by Beta-Adrenergic stimulation. Pharmacol Res Perspect, 2023 Oct;11(5):e01134 2023 Katarina Ochodnicka-Mackovicova, Michal Mokry, Martin Haagmans, Ted E. Bradley, Carel J.M. van Noesel, Jeroen E.J. Guikema. RAG1/2 induces double-stranded DNA breaks at non-Ig loci in the proximity of single sequence repeats in developing B cells. Manuscript under revision at European Journal of Immunology 2024 Katarina Ochodnicka-Mackovicova, Martine van Keimpema, Marcel Spaargaren, Rudi W. Hendriks, Carel van Noesel, Jeroen J.E. Guikema. DNA damage-induced p53 downregulates expression of RAG1 though a negative feedback loop involving miR-34a and FOXP1. Manuscript under consideration at Journal of Biological Chemistry 2024 Role of RAG1 and RAG2 in pre-B cell development, signaling and (off)target DNA damage. Katarina Ochodnicka-Mackovicova, Jeroen J.E. Guikema. Manuscript in preparation. 2024
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