123 Chapter 6 Laboratory results Bleeding time scores The bleeding time scores of 2/20 patients were prolonged (>10 min.), in 3/20 cases the bleeding time was between 8 and 10 minutes and can be interpreted as being questionable (17) (Table 2). Correlation between self-BAT score and bleeding time was negligible (R² = 0.007) (Figure 2). No statistically significant difference was found between the group with the highest bleeding scores on the self-BAT versus the group with normal bleeding scores on the self-BAT. Routine coagulation parameters Hb, MCV, Ht, INR, Platelet count, aPTT, Fibrinogen, FVIII and VWF levels were analysed. Results of Ht, INR, platelet counts, and aPTT measurements were normal and therefore will not be discussed further. Fibrinogen was abnormal in 1/20 patient; this patient had no other abnormalities in the blood tests. High FVIII activity (>150%) was found in 3/20 patients. FVIII, VWFag and VWFact results were greatly reduced in one case. However, after reassessment, no abnormalities were found. Low normal results for FVIII, VWFag and VWFact were found in three cases, for one of which a re-determination had to be done. Hb levels were significantly lower for the group with the highest scores on the self-BAT (p = 0.017). Additionally, Ht levels were significantly lower for the group with the highest scores on the self-BAT (p = 0.014). But when Ht and Hb levels were corrected for gender, there was no statistical significance between both groups. No statistically significant difference was found for MCV, INR, platelet count, aPTT, fibrinogen, FVIII, VWFag and VWFact levels between the group with the highest bleeding scores on the selfBAT versus the group with normal bleeding scores of the self-BAT. Platelet function Deviating platelet function was detected in 6/20 cases (30%). Of the six deviating scores, one was strongly deviated and this remained so even after re-determination. EPI levels were increased in 4/11 cases of the group with the highest self-BAT scores, no abnormalities were found in the group with normal bleeding scores on the self-BAT. ADP levels were increased in 4/11 cases of the group with the highest bleeding scores on the self-BAT and 2/9 cases of the group with the normal bleeding scores. No statistically significant difference was found for EPI and ADP levels between the group with high versus normal bleeding scores of the self-BAT.
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