35 Chapter 2 Physical domains OI (all types) (n = 322) P Value Type 1 (n = 220) P Value OI type 3 (n = 40) P Value OI type 4 (n = 62) P Value General population (n = 1063 + 1742) PF 57 ± 31.3 .000 63.6 ± 28.6 .000 18.4 ± 21.8 .000 57.2 ± 28.4 .000 79.4 ± 22.8 RP 50 (0; 100) .000 50 (0; 100) .000 50 (0; 100) .000 75 (0; 100) .012 76.5 ± 36.3 BP 60.4 ± 27.2 .000 59.4 ± 27.8 .000 60.4 ± 25.5 .000 64 ± 26 .000 77.14 ± 24.4 GH 54.8 ± 20.7 .000 54.6 ± 20.4 .000 50.4 ± 23.9 .000 58.2 ± 19.3 .000 69.42 ± 21.14 PCSS 39.6 ± 11.6 .000 40.6 ± 11.8 .000 31.8 ± 9.2 .000 41 ± 10.4 .000 50 ± 10 Mental Domains Vitality 58 ± 20.6 .000 56.1 ± 20.5 .000 61.7 ± 20.6 .081 62.2 ± 20.4 .043 67.53 ± 19.9 SF 75 (50; 100) .000 75 (50; 100) .000 62.5(37.5;87.5) .000 75 (62.5; 100) .066 84 ± 22.3 RE 100 (66; 100) .018 100 (66; 100) .064 100 (66; 100) .438 100 (66; 100) .210 82.57 ± 33.3 MH 74.2 ± 18 .012 73.6 ± 18 .009 75.3 ± 18.9 .618 75.6 ± 17.7 .600 76.8 ± 17.56 MCSS 49.7 ± 11.2 .615 48.7 ± 10.9 .087 53.2 ± 11.2 .078 51 ± 11.6 .492 50 ± 10 Data shown as mean ± SD or median (interquartile range) as appropriate. p Values are osteogenesis imperfecta vs general population (summary independent t test or one-sample Wilcoxon signed-rank test). Values indicating floor (≥15% with a score of 0) and ceiling (≥15% with a score of 100) effects are in bold face. BP = Bodily pain; GH = general health; MCSS = mental component summary score; MH = mental health; PCSS = physical component summary score; PF = physical functioning; RE = role functioning emotional; RP = role functioning physical; SF = social functioning. Table 1 SF-36 scores in OI types and in the general population Osteogenesis Imperfecta type
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