Ramzi Khalil

7 General discussion and future perspectives 131 36. de Andrea CE, Prins FA, Wiweger MI, Hogendoorn PC. Growth plate regulation and osteochondroma formation: insights from tracing proteoglycans in zebrafish models and human cartilage. J Pathol. 2011;224(2):160-8. 37. Hogendoorn PC, de Heer E, Weening JJ, Daha MR, Hoedemaeker PJ, Fleuren GJ. Glomerular capillary wall charge and antibody binding in passive Heymann nephritis. The Journal of laboratory and clinical medicine. 1988;111(2):150-7. 38. Gundersen HJ, Seefeldt T, Osterby R. Glomerular epithelial foot processes in normal man and rats. Distribution of true width and its intra- and inter-individual variation. Cell Tissue Res. 1980;205(1):147-55. 39. Ebarasi L, He L, Hultenby K, Takemoto M, Betsholtz C, Tryggvason K, et al. A reverse genetic screen in the zebrafish identifies crb2b as a regulator of the glomerular filtration barrier. Developmental biology. 2009;334(1):1-9. 40. Hentschel DM, Mengel M, Boehme L, Liebsch F, Albertin C, Bonventre JV, et al. Rapid screening of glomerular slit diaphragm integrity in larval zebrafish. American journal of physiology Renal physiology. 2007;293(5):F1746-50. 41. Schurer JW, Hoedemaeker J, Molenaar I. Polyethyleneimine as tracer particle for (immuno) electron microscopy. J Histochem Cytochem. 1977;25(5):384-7. 42. Rosenzweig LJ, Kanwar YS. Removal of sulfated (heparan sulfate) or nonsulfated (hyaluronic acid) glycosaminoglycans results in increased permeability of the glomerular basement membrane to 125I-bovine serum albumin. Lab Invest. 1982;47(2):177-84. 43. Hanke N, Staggs L, Schroder P, Litteral J, Fleig S, Kaufeld J, et al. “Zebrafishing” for novel genes relevant to the glomerular filtration barrier. BioMed research international. 2013;2013:658270. 44. Laurent TC, Sundelof LO, Wik KO, Warmegard B. Diffusion of dextran in concentrated solutions. Eur J Biochem. 1976;68(1):95-102. 45. Hanke N, King BL, Vaske B, Haller H, Schiffer M. A Fluorescence-Based Assay for Proteinuria Screening in Larval Zebrafish (Danio rerio). Zebrafish. 2015;12(5):372-6. 46. Rider SA, Bruton FA, Collins RG, Conway BR, Mullins JJ. The Efficacy of Puromycin and Adriamycin for Induction of Glomerular Failure in Larval Zebrafish Validated by an Assay of Glomerular Permeability Dynamics. Zebrafish. 2018;15(3):234-42. 47. Salmon AH, Satchell SC. Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability. J Pathol. 2012;226(4):562-74. 48. Miner JH. Glomerular filtration: the charge debate charges ahead. Kidney Int. 2008;74(3):25961. 49. Nayak BR, Spiro RG. Localization and structure of the asparagine-linked oligosaccharides of type IV collagen from glomerular basement membrane and lens capsule. J Biol Chem. 1991;266(21):13978-87. 50. Bernard MA, Hogue DA, Cole WG, Sanford T, Snuggs MB, Montufar-Solis D, et al. Cytoskeletal abnormalities in chondrocytes with EXT1 and EXT2 mutations. J Bone Miner Res. 2000;15(3):442-50. 51. Lin X, Wei G, Shi Z, Dryer L, Esko JD, Wells DE, et al. Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Developmental biology. 2000;224(2):299-311. 52. Xu D, Esko JD. Demystifying heparan sulfate-protein interactions. Annual review of biochemistry. 2014;83:129-57. 53. Garsen M, Rops AL, Rabelink TJ, Berden JH, van der Vlag J. The role of heparanase and the endothelial glycocalyx in the development of proteinuria. Nephrol Dial Transplant. 2014;29(1):49-55. 54. Harvey SJ, Jarad G, Cunningham J, Rops AL, van der Vlag J, Berden JH, et al. Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity. Am J Pathol. 2007;171(1):139-52.

RkJQdWJsaXNoZXIy MTk4NDMw