2 Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction 31 Figure 6. Functional evaluation of glomerular permeability and tubular reabsorption of ctns‒/‒ larvae. (a-c) Eye fluorescence assay: peak fluorescence intensity in the retinal vascular bed of ctns‒/‒ zebrafish larvae and wild-type larvae (N=20 each). Fluorescence intensities were evaluated using fixed diameter circles by the ImageJ software. (a) A representative wild-type 4 dpf larva(24h post-injection) (bar=200 µm). (b) A representative ctns‒/‒4 pdf larva(24h post-injection)(bar=200 µm). (c) A diagrammatic
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