Ramzi Khalil

Chapter 1. General introduction and outline	7
Chapter 2. Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction	17
Chapter 3. Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos	47
Chapter 4. Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier	65
Chapter 5. Increased dynamin expression precedes proteinuria in glomerular disease	83
Chapter 6. Transmembrane Protein 14A protects glomerular filtration barrier integrity	103
Chapter 7. General discussion and future perspectives	121
Appendices	137
Nederlandse samenvatting	138
Curriculum vitae	144
List of publications	145
Dankwoord	146

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