Pieter Simons

1 References 15. Niesters M, Dahan A, Swartjes M, Noppers I, Fillingim RB, Aarts L, al. et. Effect of ketamine on endogenous pain modulation in healthy volunteers. Pain. 2011; 152: 656–663 doi: 10.1016/j.pain.2010.12.015. 16. Jonkman K, Dahan A, Donk T van de, Aarts L, Niesters M, Velzen M van. Ketamine for pain. F1000Research. 2017; doi: 10.12688/f1000research.11372.1. 17. Brinck E, Tiippana E, Heesen M, Bell RF, Straube S, Moore RA, Kontinen V. Perioperative intravenous ketamine for acute postoperative pain in adults. Cochrane Database of Systematic Reviews. 2018; doi: 10.1002/14651858.cd012033.pub4. 18. Bansal A, Miller M, Ferguson I, Burns B. Ketamine as a Prehospital Analgesic: A Systematic Review. Prehospital and Disaster Medicine. 2020; 35: 314–321 doi: 10.1017/s1049023x20000448. 19. Olofsen E, Dahan A. Population pharmacokinetics/pharmacodynamics of anesthetics. The APPS Journal. 2005; 7: E383–9 doi: 10.1208/aapsj070239. 20. Smith JS, Lefkowitz RJ, Rajagopal S. Biased signalling: from simple switches to allosteric microprocessors. Nature Reviews Drug Discovery. 2018; 17: 243–260 doi: 10.1038/nrd.2017.229. 21. Raehal KM, Walker JKL, Bohn LM. Morphine side effects in -arrestin 2 knockout mice. J Pharmacol Ther. 2005; 314: 1195–2001 doi: 10.1124/jpet.105.087254. 22. Stahl EL, Bohn LM. Low intrinsic efficacy alone cannot explain the improved side effect profiles of new opioid agonists. Biochem. 2021; doi: 10.1021/acs.biochem.1c00466. 23. Ribeiro MJ, Sacramento JF, Gonzalez C, Guarino MP, Monteiro EC, Conde SV. Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets. Diabetes. 2013; 62: 2905– 16 doi: 10.2337/db12-1463. 24. Cunha-Guimaraes JP, Guarino MP, Timoteo AT, Caires I, Sacramento JF, Ribeiro MJ, Selas M, Santiago JCP, Mota-Carmo M, Conde SV. Carotid body chemosensitivity: early biomarker of dysmetabolism in humans. European Journal of Endocrinology. 2020; 182: 549–557 doi: 10.1530/EJE-19-0976. 11

RkJQdWJsaXNoZXIy MTk4NDMw