Figure 3.3: Goodness-of-Fit plots. A-Celectrical pain numerical rating scale; D-F heat pain numerical rating scale; G-I pressure pain threshold. A, D, and G: measured versus individual predicted; B, E, and H: individual weighted residuals versus time. C, FandI: normalized prediction discrepancy errors versus time. Dashed lines are the 95% confidence intervals. Open circles denote data from the 50 mg Sketamine oral thin film, closed circles data from the 100 mg S-ketamine oral thin film. 52
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