4 Chapter 4 Respiratory effects of biased-ligand oliceridine in older volunteers: a pharmacokinetic-pharmacodynamic comparison with morphine Pieter Simons1, Rutger van der Schrier1, Maarten van Lemmen1, Simone Jansen1, Kiki WK Kuijpers1, Monique van Velzen1, Elise Sarton1, Todd Nicklas2, Cathy Michalsky2, Mark A Demitrack2, Michael Fossler2, Erik Olofsen1, Marieke Niesters1, Albert Dahan13 Anesthesiology 2023; 138:249–63 1. Department of Anesthesiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands 2. Trevena Inc., Chesterbrook, PA, USA 3. PainLess Foundation, Leiden, the Netherlands
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