APPENDIX I: RISK OF BIAS ASSESSMENT Study SelecSon SelecSon SelecSon Performance ATriSon DetecSon DetecSon ReporSng Clear inclusion criteria Random sequence alloca~on done Analysed in defined group Rule out concurrent interven~on Small loss to follow up Defini~on of outcomes stated Blinding of assessor Repor~ng of all specified outcomes Azer et al.18 Yes N/A Yes No No Yes Yes Yes Bonrath et al.26 Yes Yes Yes No Yes Yes Yes Yes Buchwald et al.2 Yes N/A Yes N/A Yes N/A N/A Yes Davis et al.5 Yes N/A Yes No Unclear Yes Yes Yes Fanous et al.6 No No Yes Yes Yes Yes Yes Unclear Harrington et al.25 No No Yes N/A Yes Yes No Yes Iordens et al.23 Yes No Yes Yes Yes yes No Yes Leandros et al.19 Yes N/A Yes Yes Unclear Yes Yes Yes Mar~n et al.28 Yes Yes Yes No Yes No No Yes Moran-Atkin et al.27 Yes Yes Yes No No Yes Yes Unclear Rovito et al.24 No No Yes No Unclear Unclear No Unclear Varas et al.20 Yes No Yes No Yes yes No Yes Zevin et al.21 N/A N/A N/A N/A N/A N/A N/A N/A Zimmerman et al.22 Yes N/A Yes Yes Unclear yes Yes Yes N/A = Not applicable 40 2
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