119 Distinct brain MRI phenotypes and their association with long-term dementia risk 6 Figure 6.2 Heatmap and Dendrogram: Results of the Hierarchical Clustering Analysis Red indicates high values, and blue indicates low values. Every line represents a participant, and every column represents a MRI marker. 1: total WMH volume; 2: PV/C WMH volume; 3: PV/C WMH volume frontal lobe; 4: other PV/C WMH volume; 5: PV/C WMH fractal dimension; 6: PV/C WMH volume parietal lobe; 7: PV/CWMH volume temporal lobe; 8: PV/C WMH concavity index; 9: % lateral ventricle volume; 10: PV/C WMH volume occipital lobe; 11: deep WMH volume; 12: deep WMH volume frontal lobe; 13: number of deep WMH; 14: deep WMH volume parietal lobe; 15: other deep WMH volume; 16: deep WMH volume temporal lobe; 17:%total brain volume; 18: % gray matter volume; 19: PV/C convexity; 20: % white matter volume; 21: deep WMH eccentricity; 22: deep WMH fractal dimension; 23: PV/C solidity; 24: deep WMH occipital lobe; 25: number of PV/C; 26: enlarged perivascular spaces in and around basal ganglia; 27: microbleeds; 28: cortical infarcts; 29: subcortical infarcts; 30: enlarged perivascular spaces in the white matter; 31: infarcts (whole brain); 32: cerebellar infarcts. Other PV/C WMH volume or other deep WMH volume were defined as Lesions or parts of lesions that were outside of the brain lobe masks, for example the brain stem and within the internal capsule. PV/C = periventricular/confluent; S = subgroup; WMH = white matter hyperintensity.
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