12 Chapter 1 in Figure 1.1.20 High solidity and convexity, as well as low concavity index and fractal dimension reflect a more irregular shape. For deep WMH, the shape markers that were found appropriate are fractal dimension and eccentricity. Higher eccentricity suggests a more elongated shape. Periventricular/confluent WMH and deep WMH have very different shape appearances which is why different shape markers are used for each of them to most accurately capture their shape. Figure 1.1. Illustration of shapes and different shape markers. Solidity, convexity, concavity index, and fractal dimension are calculated for periventricular/confluent WMH. Eccentricity and fractal dimension are calculated for deep WMH. This Figure is modified from figure 7.3 of Chapter 7.
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