124 Chapter 6 Table 6.3. Between-group differences of brain MRI markers. S1 N=368 S2 N=161 S3 N=425 S4 N=239 S5 N=171 S6 N=333 S7 N=98 Total WMH volume 11.87 ± 4.69 35.85± 22.86 29.93 ± 16.76 7.50 ± 3.33 11.76 ± 7.66 8.02 ± 3.72 5.77 ± 2.25 PV/C WMH volume 10.68 ± 4.59 33.76 ± 22.83 28.51 ± 16.81 6.05 ± 3.10 10.28 ± 7.04 7.57 ± 3.60 4.83 ± 2.14 Deep WMH volume 1.18 ± 0.94 2.09 ± 1.52 1.42 ± 0.91 1.45 ± 0.85 1.49 ± 1.69 0.45 ± 0.39 0.94 ± 0.81 Number of PV/C 14.69 ± 5.70 14.86± 5.03 14.96 ± 5.51 14.90 ± 5.89 14.71 ± 5.07 15.27 ± 6.19 15.53 ± 6.06 Number of deep WMH 25.40 ± 15.29 44.69 ± 29.64 41.26 ± 25.69 21.23 ± 13.84 28.89 ± 26.73 16.39 ± 13.72 15.06 ± 10.83 PV/C solidity 0.18 ± 0.07 0.15 ± 0.05 0.13 ± 0.05 0.23 ± 0.11 0.21 ± 0.13 0.20 ± 0.11 0.25 ± 0.11 PV/C convexity 1.11 ± 0.12 0.87 ± 0.18 0.89 ± 0.14 1.13 ± 0.13 1.08 ± 0.14 1.13 ± 0.12 1.13 ± 0.11 PV/C concavity index 1.22 ± 0.07 1.42 ± 0.14 1.41 ± 0.11 1.17 ± 0.07 1.22 ± 0.11 1.19 ± 0.08 1.15 ± 0.07 PV/C fractal dimension 1.69 ± 0.09 1.84 ± 0.11 1.82 ± 0.08 1.65 ± 0.11 1.67 ± 0.14 1.62 ± 0.11 1.58 ± 0.12 Deep WMH eccentricity 0.56 ± 0.06 0.61 ± 0.06 0.63 ± 0.06 0.61 ± 0.07 0.62 ± 0.08 0.65 ± 0.08 0.62 ± 0.08 Deep WMH fractal dimension 1.79 ± 1.79 1.69 ± 0.12 1.65 ± 0.12 1.71 ± 0.13 1.69 ± 0.13 1.59 ± 0.12 1.69 ± 0.15 % lateral ventricle volume 2.61 ± 0.97 3.23 ± 1.09 3.60 ± 1.15 2.18 ± 0.72 2.63 ± 1.08 2.82 ± 0.93 2.19 ± 0.72 % total brain volume 74.52 ± 3.02 71.48 ± 3.59 70.80 ± 3.02 74.27 ± 2.45 72.91 ± 3.07 72.25 ± 2.82 73.44 ± 3.62 % grey matter volume 46.84 ± 2.60 44.50 ± 2.96 43.97 ± 2.62 47.28 ± 2.04 45.95 ± 2.70 45.41 ± 2.43 46.49 ± 3.09 % white matter volume 27.68 ± 1.49 26.98 ± 1.93 26.83 ± 1.35 26.98 ± 1.55 26.96 ± 1.47 26.84 ± 1.49 26.95 ± 1.54 PVS (basal ganglia) 0% 9% 8% 0% 5% 0% 4% PVS 0% 0% 0% 3% 10% 0% 100% Microbleeds 0% 14% 1% 16% 12% 0% 0% Subcortical infarcts 0% 100% 0% 0% 8% 0% 0% Cerebellar infarcts 0% 5% 0% 0% 98% 0% 0% Cortical infarcts 0% 4% 0% 0% 1% 0% 0% Infarcts 0% 100% 0% 0% 100% 0% 0% Data shown as mean ±SD or percentages of individuals per subgroup. Brain MRI markers were compared between subgroups with chi-square Test for binary variables, and one-way ANOVAs for continuous variables. The data for WMH volumes per lobe are shown in supplementary table S.6.8.2. S, subgroup; WMH, white matter hyperintensity; PV/C periventricular/confluent WMH; PVS, enlarged perivascular spaces; SD, standard deviation.
RkJQdWJsaXNoZXIy MTk4NDMw