125 Distinct brain MRI phenotypes and their association with long-term dementia risk 6 S8 N=42 S9 N=105 S10 N=241 S11 N=240 S12 N=87 S13 N=245 S14 N=190 S15 N=111 P value 6.07 ± 2.66 22.90 ± 12.89 3.20 ± 1.44 25.93 ± 15.89 50.32 ± 20.71 24.56 ± 9.63 41.11 ± 21.16 22.85 ± 16.85 <0.001 5.18 ± 2.65 21.05 ± 12.86 2.37 ± 1.29 23.93 ± 15.72 46.99 ± 20.77 21.43 ± 9.71 39.19 ± 21.46 21.29 ± 16.60 <0.001 0.89 ± 0.75 1.85 ± 1.41 0.83 ± 0.51 2.00 ± 1.27 3.33 ± 1.51 3.13 ± 1.81 1.91 ± 1.36 1.57 ± 1.35 <0.001 15.36 ± 5.94 14.78 ± 5.57 16.00 ± 5.98 14.93 ± 6.08 15.62 ± 6.12 15.23 ± 5.94 14.78 ± 5.46 14.57 ± 5.41 <0.001 14.67± 10.29 41.90 ± 22.40 8.20 ± 5.11 46.33 ± 26.79 86.90 ± 40.35 45.49 ± 16.62 46.88 ± 28.29 34.59 ± 23.67 <0.001 0.25 ± 0.12 0.13 ± 0.05 0.39 ± 0.16 0.14 ± 0.05 0.03 ± 0.15 0.14 ± 0.04 0.14 ± 0.05 0.17 ± 0.07 <0.001 1.15 ± 0.11 0.97 ± 0.16 1.12 ± 0.11 0.92 ± 0.19 0.67 ± 0.13 0.97 ± 0.14 0.81 ± 0.16 1.00 ± 0.17 <0.001 1.15 ± 0.06 1.35 ± 0.12 1.09 ± 0.06 1.38 ± 0.15 1.59 ± 0.11 1.34 ± 0.10 1.47 ± 0.13 1.31 ± 0.14 <0.001 1.58 ± 0.11 1.78 ± 0.10 1.48 ± 0.14 1.80 ± 0.11 1.92 ± 0.07 1.81 ± 0.09 1.87 ± 0.09 1.74 ± 0.12 <0.001 0.60 ± 0.10 0.61 ± 0.07 0.64 ± 0.08 0.61 ± 0.06 0.66 ± 0.05 0.58 ± 0.05 0.63 ± 0.06 0.62 ± 0.06 <0.001 1.68 ± 0.12 1.68 ± 0.13 1.72 ± 0.13 1.69 ± 0.13 1.60 ± 0.11 1.77 ± 0.08 1.66 ± 0.12 1.70 ± 0.12 <0.001 2.21 ± 0.91 3.09 ± 1.21 1.85 ± 0.64 2.92 ± 1.06 3.43 ± 0.98 2.50 ± 0.82 3.64 ± 1.21 3.08 ± 1.07 <0.001 74.93 ± 3.16 72.02 ± 3.56 75.73 ± 3.07 71.94 ± 3.60 68.76 ± 4.15 74.55 ± 2.93 70.69 ± 4.01 71.75 ± 3.09 <0.001 47.86 ± 2.32 45.06 ± 2.85 48.20 ± 2.58 44.96 ± 2.93 42.71 ± 3.40 46.76 ± 2.41 43.72 ± 3.38 44.45 ± 2.83 <0.001 27.07 ± 1.35 26.96 ± 1.74 27.53 ± 1.48 26.98 ± 1.70 26.05 ± 2.03 27.79 ± 1.63 26.97 ± 1.85 27.30 ± 1.59 <0.001 0% 0% 0% 8% 2% 0% 6% 8% <0.001 0% 17% 0% 99% 2% 0% 17% 16% <0.001 5% 66% 0% 2% 1% 0% 9% 7% <0.001 100% 0% 0% 0% 3% 0% 22% 5% <0.001 0% 0% 0% 0% 0% 0% 99% 29% <0.001 0% 0% 0% 0% 0% 0% 4% 100% <0.001 100% 0% 0% 0% 3% 0% 100% 100% <0.001
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