Jasmin Annica Kuhn-Keller

167 General Discussion 8 8.5 REFERENCES 1. Ghaznawi R, Geerlings M, Jaarsma-Coes M, Hendrikse J, de Bresser J. Association of White Matter Hyperintensity Markers on MRI and Long-term Risk of Mortality and Ischemic Stroke. Neurology 2021; : 10.1212/WNL.0000000000011827. 2. De Bresser J, Kuijf HJ, Zaanen K, Viergever MA, Hendrikse J, Biessels GJ et al. White matter hyperintensity shape and location feature analysis on brain MRI; Proof of principle study in patients with diabetes. Sci Rep 2018; 8: 1–10. 3. Ghaznawi R, Geerlings MI, Jaarsma-Coes MG, Zwartbol MHT, Kuijf HJ, van der Graaf Y et al. The association between lacunes and white matter hyperintensity features on MRI: The SMART-MR study. Journal of Cerebral Blood Flow and Metabolism 2019; 39: 2486–2496. 4. Alber J, Alladi S, Bae H, Barton DA, Beckett LA, Bell JM et al. White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities. Alzheimer’s & Dementia: Translational Research & Clinical Interventions 2019; 5: 107–117. 5. Wardlaw JM, Smith C, Dichgans M. Small vessel disease: mechanisms and clinical implications. Lancet Neurol 2019; 18: 684–696. 6. Ter Telgte A, Van Leijsen EMC, Wiegertjes K, Klijn CJM, Tuladhar AM, De Leeuw FE. Cerebral small vessel disease: From a focal to a global perspective. Nat Rev Neurol. 2018; 14: 387–398. 7. Han F, Chen J, Belkin-Rosen A, Gu Y, Luo L, Buxton O et al. The coupling of global brain activity and cerebrospinal fluid inflow is correlated with Alzheimer’s disease related pathology. 2020. doi:10.1101/2020.06.04.134726. 8. Benveniste H, Nedergaard M. Cerebral small vessel disease: A glymphopathy? Curr Opin Neurobiol 2022; 72: 15–21. 9. Hirschler L., Aldea R., Petitclerc L., Ronen I., de Koning P.J.H., van Buchem, M. A., van Osch M.J.P. High resolution T2-prepared MRI enables non-invasive assessment of CSF flow in perivascular spaces of the human brain. In: Proceedings of the 28th Annual Meeting of ISMRM, Montréal, Canada, 2019. Abstract 0746. 10. Fultz NE, Bonmassar G, Setsompop K, Stickgold RA, Rosen BR, Polimeni JR et al. Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep. Science (1979) 2019; 366: 628–631. 11. Fazekas F, Kleinert R, Offenbacher H, Schmidt R, Kleinert G, Payer F et al. Pathologic correlates of incidental MRI white matter signal hyperintensities. Neurology 1993; 43: 1683–1689. 12. Kalaria RN, Kenny RA, Ballard CG, Perry R, Ince P, Polvikoski T. Towards defining the neuropathological substrates of vascular dementia. J Neurol Sci 2004; 226: 75–80. 13. Fernando MS, Simpson JE, Matthews F, Brayne C, Lewis CE, Barber R et al. White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injury. Stroke 2006; 37: 1391–1398.

RkJQdWJsaXNoZXIy MTk4NDMw