Jasmin Annica Kuhn-Keller

53 White matter hyperintensity shape and long-term progression of cerebrovascular disease 3 3.9 SUPPLEMENTARY MATERIAL Table S.3.9.1. Baseline characteristics of the participants included and excluded from our study. Included participants (n= 2297) Excluded participants (n= 2317) p-values Age at baseline (years) 74.5 ± 4.7 78.3 ± 5.6 <0.001 Females 1399 (61%) 1281 (55%) <0.001 Hypertension 1763 (77%) 2226 (96%) <0.001 Type 2 diabetes mellitus 192 (8%) 324 (14%) <0.001 BMI at baseline (kg/m3) 27.2 ± 4.1 26.8 ± 4.6 <0.001 Cholesterol (mmol/L) 5.70 ± 1.13 5.58 ± 1.18 <0.001 Smoking status Never 1017 (44%) 979 (42%) 0.166 Former 1030 (45%) 1031 (45%) 0.178 Current 250 (11%) 304 (13%) 0.019 Coronary artery disease 361 (16%) 760 (33%) <0.001 Data are shown as mean ± SD or frequency (%). Baseline characteristics were collected via questionnaires. One-way ANOVA’s were performed for continuous variables, and Chi-square tests for categorical variables.

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