Martijn Sijbom

119 Cues to improve antibiotic-allergy registration: A mixed-method stu 5 The primary goals of this study were to analyze the quality of antibiotic allergy registrations in primary care and to identify determinants related to the quality of registration in all involved healthcare domains. Methods Study design The study consisted of a point prevalence analysis of the quality of antibiotic allergy registrations in primary care, together with a qualitative study based on semistructured interviews to assess the determinants of incorrect registration. Before the start of this study, the study was approved by the institutional Ethics Review Board of the Leiden University Medical Center (file number G19.007). Analysis of the quality of antibiotic allergy registrations in primary care Data collection Patient data were obtained through the Extramural LUMC Academic Network (ELAN), which includes 31 primary care practices in the Leiden-The Hague area and holds primary care data of approximately 200,000 patients. Primary care physicians involved in this network provide access to their anonymized EMRs medical data, that are accessible through the ELAN data warehouse. Antibiotic allergy registrations were identified based on the following registrations in the EMR: International Classification of Primary Care version 1 (ICPC) code A12 (allergy/allergic reaction) or A85 (adverse event medical agent) or a registration for a contraindication (CIA) label antibiotic allergy for Anatomical Therapeutic Chemical (ATC) code J01 (antibacterials for systemic use). The EMR in primary care supports registration of all relevant details within the allergy label, including symptoms and time course of the reaction. All registrations dated up until the year 2018 were used. EMRs from primary care and pharmacies are linked and exchange information on antibiotic allergies automatically. The primary care antibiotic allergy label is not electronically linked to the EMR in hospitals nor long term care facilities. Information on allergy labels between primary care and hospitals/long term care facilities is exchanged through referral letters.

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