Martijn Sijbom

39 Trends in antibiotic selection pressure generated in primary care and their association with sentinel antibiotic resistance patterns in Europe 2 Supplements Supplement 1. STROBE-AMS checklist Item Item number STROBE recommendation Pag STROBE-AMS new items Pag Introduction Background/ rationale 2 Explain the scientific background and rationale for the investigation being reported Yes 2.1 Report previous clinical in vivo and in vitro studies 4 Objectives 3 State specific objectives, including any prespecified hypotheses Yes 4 Methods Setting 5 Describe the setting, locations, relevant dates, including periods of recruitment, exposure, follow-up and data collection 5.1 Describe if setting is epidemic or endemic (high, low, medium) for the study outcome 5.2 Specify type of hospital or unit and characteristics of population served by the healthcare setting 5.3 Describe antimicrobial formulary in use at the study location related to the analysed antibiotics 5.4 Describe infection control measures dedicated to the target resistant bacteria applied at the study location 5 Participants 6 (a) Cohort study—Give the eligibility criteria, the sources and methods of selection of participants. Describe methods of follow-up Case–control study—Give the eligibility criteria, the sources, methods of case ascertainment and control selection. Give the rationale for the choice of cases and controls Cross-sectional study—Give the eligibility criteria, the sources and methods of selection of participants (b) Cohort study—For matched studies, give matching criteria, the number of exposed and unexposed Case–control study—For matched studies, give matching criteria and the number of controls per case 6.1 Define unit analysed (person, department or other) 6.2 Provide reasons (epidemiological and clinical) for choosing matching criteria NA NA

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