183 Impact of anastomotic leakage after colorectal cancer surgery on quality of life: A systematic review Table 1. Continued Reference Year Country Study design Study period No. of patients Inclusion criteria Exclusion criteria Aim of the study Miura et al. 2017 Japan Retrospective cohort study 2000 - 2012 275 Low rectal adenocarcinoma Diverting stoma To evaluate permanent stoma formation and defecation in long-term follow up after surgery for low rectal cancer without a diverting stoma. Mongin et al. 2014 France Retrospective casematched study 2004 - 2010 63 Laparoscopic TME for rectal cancer with a follow-up of ≥ 6 months and consent to fill in the questionnaires Permanent or temporary stoma To assess the influence of AL on long-term functional results and QoL after laparoscopic TME for cancer. di Re et al. 2022 Australia Retrospective casematched study 2010 - 2020 122 - AL - Adult population - Benign or malignant colorectal disease IBD, pouch formation and redo resections To assess bowel function and QoL after AL from rectal resections. Riss et al. 2011 Austria Retrospective casematched study 1995 - 2006 32 - TME for rectal cancer - Control group: uneventful postoperative course Died during follow-up and no response to questionnaire To investigate the impact of AL after rectal resection for malignancies on overall pelvic organ function and QoL. Westerduin et al. 2021 The Netherlands, Belgium and France Retrospective comparative cohort study 2007 - 2017 170 - TME for rectal cancer - All indications for redo anastomosis - Control group: successful primary anastomosis Partial mesorectal excision, stoma at the time of questionnaire, unable to read or understand the questionnaires To compare functional outcomes and the QoL between redo anastomosis and primary successful anastomosis following TME for rectal cancer. *Post-hoc analysis of a prospective multicentre randomized controlled trial AL, anastomotic leakage; CRC, colorectal cancer; HRQoL, Health-related Quality of Life; IBD, Inflammatory Bowel Disease; QoL, Quality of Life; TME, Total Mesorectal Excision. 9
RkJQdWJsaXNoZXIy MTk4NDMw