193 Impact of anastomotic leakage after colorectal cancer surgery on quality of life: A systematic review Table 3. Continued Reference Time of assessment after surgery Questionnaire Significant impaired domains (in favor of non-AL patient) P values Groups compared McGiffin et al. > 2 years (Median 6.4 (IQR 3.1–8.6) and 4 years (IQR 2.7–8.5) for no AL and AL group respectively SF-36 PCS NA NS AL vs non-AL after rectal surgery at time of assessment (no baseline assessment) SF-36 MCS NA NS Miura et al. Variable, at time of the study (Median 63.5 and 63 months for no AL and AL group respectively) mFIQL NA NS AL vs non-AL after rectal surgery at time of assessment (no baseline assessment) Mongin et al. > 6 months after restoration of bowel continuity (Median 33 months (IQR 6 – 75) and 30 months (IQR 6-70) for no AL and AL group respectively) SF-36 PCS NA NS AL vs non-AL after rectal surgery at time of assessment (no baseline assessment) SF-36 MCS NA NS di Re et al. Variable, at time of the study (Range 1 to > 5 years) EQ-VAS NA NS AL vs non-AL after colorectal surgery at time of assessment (no baseline assessment) Riss et al. Variable, at time of the study (Median 106.8 months (range 32.4-170.4)) SF-12 NA NS AL vs non-AL after rectal surgery at time of assessment (no baseline assessment) 9
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