41 Quality of reporting on anastomotic leaks in colorectal trials: A systematic review Table 1. Continued Author Year Country Study design Number of patients* Number of studies Aim of the study Type of resections included Ulrich et al. 101 2009 Germany RCT 34 N/A To evaluate the need for diverting ileostomy in patients undergoing LAR. LAR Van’t Sand et al. 102 2011 The Netherlands RCT subgroup analysis 63 N/A To evaluate the effects of MBP on morbidity and mortality after AL in elective colorectal surgery. All types of colorectal procedures Wang et al. 103 2017 China SR and MA 11535 14 To evaluate the impact of AL on disease recurrence and survival. AR Wang et al. 104 2016 China SR and MA 909 4 To evaluate the efficacy of TDT placement after AR. AR Whistance et al. 105 2013 UK SR N/A 194 To summarize and undertake an in-depth analysis of outcome reporting in CRC surgery. All types of colorectal procedures Wiggins et al. 106 2015 UK SR and MA 2296 6 To compare the outcomes of gastrointestinal anastomosis with and without the use of omentoplasty. All types of colorectal procedures Wright et al. 107 2017 UK SR N/A 13 To appraise the current evidence base into local biomarkers of AL allowing the identification of the most promising emerging biomarkers and discussion of their limitations and future potential clinical role All types of colorectal procedures Wu et al. 108 2014 China MA 5612 11 To provide a comprehensive evaluation of the role of a protective stoma in LAR for rectal cancer. LAR Xiao et al. 109 2011 China RCT 398 N/A To investigate whether the use of a TDT as an alternative endoluminal diversion technique for rectal carcinoma can reduce the 30-day leakage rate after LAR. LAR 2
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