86 Chapter 3 AND (controlled[tiab] OR control[tiab] OR placebo[tiab] OR versus[tiab] OR vs[tiab] OR group[tiab] OR groups[tiab] OR comparison[tiab] OR compared[tiab] OR crossover[tiab] OR cross-over[tiab]) AND (trial[tiab] OR study[tiab])) OR ((single[tiab] OR double[tiab] OR triple[tiab]) AND (masked[tiab] OR blind*[tiab])))))) NOT (((“Animals”[MeSH]) OR “Models, Animal”[MeSH] NOT “Humans”[MeSH]) NOT (letter[pt] OR comment[pt] OR editorial[pt])) • Embase: (exp colorectal tumor/ or exp colorectal cancer/ or ((neoplasm/ or (carcinoma* or adenocarcinoma* or neoplas* or tumour* or tumor* or oncolog* or malignan* or cancer*).ti,ab,kw.) adj3 (colorectal* or colon or colonic or rectal or rectum or sigmoid*). ti,ab,kw.)) and (exp colorectal surgery/ or exp rectum surgery/ or exp colon surgery/ or ileoanal anastomosis/ or ileorectal anastomosis/ or ((large bowel or colorectal* or colon or rectum or rectal or ileocaecal or caecum or low anterior).ti,ab,kw. adj3 (resection* or surg* or anastomo*).ti,ab,kw. or (colectom* or hemicolectom* or “total mesorectal excision*” or proctocolectom* or “abdominal perineal resection*”).ti,ab,kw.)) and (postoperative complication/su or exp anastomosis leakage/ or anastomosis/co or (anastomo* adj3 (leak* or complication*)).ti,ab,kw.) and (((“systematic review”/ or (systematic review.ti. or systematic literature review.ti. or systematic scoping review.ti. or systematic narrative review.ti. or systematic qualitative review.ti. or systematic evidence review.ti. or systematic quantitative review.ti. or systematic meta-review.ti. or systematic critical review.ti. or systematic mixed studies review.ti. or systematic mapping review. ti. or systematic cochrane review.ti. or “systematic search and review”.ti. or systematic integrative review.ti.)) or (meta analysis/ or meta analysis.ti.) or (randomized controlled trial/ or ((random*.ti,ab. and (controlled.ti,ab. or control.ti,ab. or placebo.ti,ab. or versus. ti,ab. or vs.ti,ab. or group.ti,ab. or groups.ti,ab. or comparison.ti,ab. or compared.ti,ab. or crossover.ti,ab. or cross-over.ti,ab.) and (trial.ti,ab. or study.ti,ab.)) or ((single.ti,ab. or double.ti,ab. or triple.ti,ab.) and (masked.ti,ab. or blind*.ti,ab.))))) NOT ((exp animal/ or nonhuman/) NOT exp human/) NOT (letter or editorial).pt.) • Cochrane: (“Colorectal Neoplasms”[MeSH] OR ((“Neoplasms”[MeSH] OR carcinoma*:ti,ab,kw OR adenocarcinoma*:ti,ab,kw OR neoplas*:ti,ab,kw OR tumour*:ti,ab,kw OR tumor*:ti,ab,kw OR oncolog*:ti,ab,kw OR malignan*:ti,ab,kw OR cancer*:ti,ab,kw) AND (colorectal*:ti,ab,kw OR colon:ti,ab,kw OR colonic:ti,ab,kw OR rectal:ti,ab,kw OR rectum:ti,ab,kw OR sigmoid*:ti,ab,kw))) AND (“Colectomy”[MeSH] OR “Colorectal Surgery”[MeSH] OR “Rectum/surgery”[MeSH] OR “Colon/surgery”[MeSH] OR ((large bowel:ti,ab,kw OR colorectal*:ti,ab,kw OR colon:ti,ab,kw OR rectum:ti,ab,kw OR rectal:ti,ab,kw OR ileocaecal:ti,ab,kw OR caecum:ti,ab,kw OR low anterior:ti,ab,kw) AND (resection*:ti,ab,kw OR surg*:ti,ab,kw OR anastomo*:ti,ab,kw OR “Anastomosis, Surgical”[MeSH])) OR (colectom*:ti,ab,kw OR hemicolectom*:ti,ab,kw OR “total mesorectal excision*”:ti,ab,kw OR proctocolectom*:ti,ab,kw OR “abdominal perineal resection*”:ti,ab,kw)) AND (“Anastomotic Leak”[MeSH] OR (anastomo*:ti,ab,kw AND (“adverse effects”[Subheading] OR “complications”[Subheading] OR leak*:ti,ab,kw OR complication*:ti,ab,kw OR defect*:ti,ab,kw OR separation*:ti,ab,kw OR dehiscence*:ti,ab,kw OR breakdown*:ti,ab,kw OR abscess*:ti,ab,kw))
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