48 CHAPTER 3 S2: CHARACTERISTICS OF COVID-19 PATIENTS AND THEIR RELATION TO THE DEVELOPMENT OF NEW-ONSET ATRIAL FIBRILLATION OR ATRIAL FLUTTER DURING HOSPITALISATION. No AF/AFLa (n=4,712) AF/AFLa (n=420) Unadjusted odds ratio (95% CI) Demographics, risk factors, medical history, medication (before hospital admission) Male sex n (%) 2,955 (62.7) 294 (70.0) 1.38 (1.12-1.73) Sex NA n (%) 1 (0.0) 0 (0.0) Age in years 64 (54-74) 73 (66-79) 1.15 (1.07-1.28) Age in years’ median (IQR)b 0.92 (0.80-1.04) Age in years’’ 1.05 (0.67-1.80) Age in years NA n (%) 0 (0.0) 0 (0.0) BMI in kg/m2 median (IQR)b 27.47 (24.62-30.93) 27.19 (24.69-30.46) 1.06 (0.96-1.18) BMI in kg/m2’ 0.83 (0.53-1.26) BMI in kg/m2’’ 1.47 (0.42-5.27) BMI in kg/m2 NA n (%) 1252 (26.6) 62 (14.8) Heart failure n (%) 156 (3.3) 23 (5.5) 1.72 (1.05-2.64) Heart failure NA n (%) 10 (0.2) 1 (0.2) Hypertension n (%) 2,031 (44.0) 227 (55.4) 1.57 (1.29-1.93) Hypertension NA n (%) 101 (2.1) 10 (2.4) Diabetes mellitus (type I or II) n (%) 1,195 (25.6) 100 (24.2) 0.93 (0.73-1.17) Diabetes mellitus (type I or II) NA n (%) 51 (1.1) 7 (1.7) Peripheral arterial disease n (%) 181 (4.9) 26 (8.0) 1.70 (1.07-2.55) Peripheral arterial disease NA n (%) 1,033 (21.9) 94 (22.4) Myocardial infarctionc n (%) 374 (8.0) 47 (11.3) 1.47 (1.04-2.00) Myocardial infarctionc NA n (%) 56 (1.2) 3 (0.7) Renal impairment n (%) 414 (8.8) 58 (13.9) 1.69 (1.24-2.24) Renal impairment NA n (%) 6 (0.1) 3 (0.7) Digoxin n (%) 19 (0.4) 12 (2.9) 7.36 (3.40-14.91) Digoxin NA n (%) 4 (0.1) 0 (0.0)
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