2 99 REVIEW OF APPLIED & CASUAL GAMES FOR MENTAL HEALTH Paper Country Target group N % male Age, mean (SD) Age range Intervention arms Intervention characteristics Assessments Variables measured Findings relevant for current review Schuurmans, Nijhof, Scholte et al. 2021 The Netherlands Adolescents with clinical levels of post-traumatic symptoms 77 59.7 15.25 (1.79) 10-18 years 1. Muse, gamebased and neurofeedback meditation intervention in addition to TAU. 2. Treatment as usual. 1. Two individual 15-20 minutes gameplay sessions a week, for 6 consecutive weeks. 2. TAU consisted of evidence-based treatments that did not specifically target post-traumatic symptoms. Pre, post and 2-months FU. Basal autonomic nervous system measures and parasympathetic nervous system activity (SNS and PNS), basal hypothalamic-pituitary-adrenal (HPA) axis activity (hair cortisol), neurobiological reactivity to acute stress during a social stress task (autonomic nervous system parameters and saliva cortisol); concomitant interventions, smoking, alcohol and caffeine use, sporting behaviour, eating behaviour medication use, comorbid psychological and physiological disorders, hormonal contraception, menstrual cycle phase, sleep, season, time of testing, storage time, age, hair treatment, hair washing (covariates). The Muse group exhibited lower basal activity for the SNS and increased HPA reactivity to acute stress. No differences between groups were found on SNS and HPA axis activity during rest and on SNS and PNS reactivity to acute stress. Tsui et al. 2021 Canada Youth with anxiety symptoms 116*c 33.3 13.50 (1.58) 8-15 years 1. MindLight (applied game). 2. online CBT (active condition). Both conditions: five one-hour sessions within a 3-week period. Pre, post, and 3-months FU. Anxiety symptoms, state anxiety after stress task, psychophysiological arousal during stress tasks (heartrate); age (moderator). Anxiety significantly decreased over time in both conditions. Youth in the MindLight condition showed greater pre-to-post reductions in anxiety symptoms.
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