192 Part C: Application Cycle During the application cycle, we delved into the practical application of the IeG within a specific real-world scenario: The development of a tailored eHealth intervention for people with a low SEP in the context of cardiac rehabilitation (CR). Chapter 5 presents the design process of this intervention in which we identified the need of patients with a low SEP to feel more certain and guided during their waiting period preceding CR. In response, we developed a tailored eHealth intervention, together with the target group, to address this need. Implementing the guide during this project yielded four key lessons learned that could guide future designers in similar case-specific applications of the IeG: the need for resource management, the value of participatory methods, and the importance of personalization and simplicity in eHealth design. In Chapter 6, we evaluated the feasibility and effects on certainty and guidance of the developed intervention among people with a low SEP. Results show the potential of the intervention and the IeG. The intervention demonstrated good adherence and acceptance among participants. Despite the quantitative data showing no improvements in certainty and guidance, qualitative insights suggest that the intervention may offer benefits in these areas. The results show that the application of the IeG could lead to the development of interventions that are both adhered to and accepted by people with a low SEP, posing it as a valuable resource for professionals designing equitable eHealth interventions. Conclusion This dissertation contributes to narrowing the health gap by developing and applying the IeG, a practical tool for designing equitable eHealth interventions. We identified diverse subgroups within low SEP, each with specific needs. There are the optimistically engaged who could benefit most from a blended system that maintains and emphasizes the personal connection with healthcare providers. The doubtfully disadvantaged have a lot to gain from eHealth and can be supported through simplifying medical content, ensuring good usability, and fostering a sense of achievement and control. Additionally, there is the complexly challenged group, which is the most difficult to reach through eHealth, and could benefit more from the integration of socio-economic and community support programs. Furthermore, our findings underscore the importance of bridging theoretical knowledge with practical application, exemplified by the IeG and our practical case study. Finally, this dissertation has shed light on some important implications for design and design processes. Regarding the design process, we can confirm that participatory
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