104 Chapter 7 Table 2. Risk factors associated with implant loss within the training cohort Risk factors Group Event rate (%) Unadjusted OR (95% CI) P-value Adjusted OR (95% CI) P-value BMI* - - 1 1.050 (1.023-1.077) <0.001 1 1.050 (1.023-1.077) <0.001 Current smoker No Yes 189 (6.5) 55 (12.6) 1 2.081 (1.513-2.862) <0.001 1 2.081 (1.513-2.862) <0.001 Previous radiotherapy No Yes 247 (7.0) 18 (9.6) 1 1.403 (0.848-2.319) 0.187 1 1.811 (1.064-3.081) 0.029 Prepectoral placement No Yes 218 (6.6) 42 (12.0) 1 1.911 (1.346-2.713) <0.001 1 1.911 (1.346-2.713) <0.001 Volume permanent implant** - - 1 1.306 (1.109-1.539) 0.001 1 1.306 (1.109-1.539) 0.001 Univariate and multivariate analysis of risk factors associated with implant loss within the training cohort, resulting in unadjusted and adjusted ORs, confidence intervals and corresponding P-values (significant values are denoted in italic). Event rate describes the rate of implant loss in reconstructions with and without the corresponding risk factor. BMI indicates body mass index; CI, confidence interval; OR, odds ratio; TE, tissue expander. *OR was calculated per 1 kg/m increment **Data of permanent implants within training cohort (n=968). OR was calculated per 100cc increase of volume.
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