Yara Blok

43 Pectoral fascia preservation in oncological mastectomy Salgarello et al reported two chest wall recurrences (1.1%). No data on regional recurrences, distant metastasis, nor mortality rates were provided.13 Complications Postoperative bleeding Information on bleeding complications was provided in two publications.13, 16 In the study of Sandelin et al, only the bleeding complications that required reoperation were reported, being 2 of n=188 patients (1.1%) who underwent implant reconstruction, and 3 of n=13 patients (23.1%) who underwent TRAM flap reconstruction, in which the location of the bleeding was not further specified.16 Salgarello et al reported the presence of postoperative hematoma in six of 256 (2.7%) mastectomies, of whom four (1.8%) required reoperation (Table 3).13 Seroma Occurrence of seroma was compared between the two mastectomy groups in the trial by Dalberg et al, in which seroma was defined as any clinically detected collection of fluid requiring aspiration in the axilla or anywhere along the skin incisions. Data on the occurrence of seroma were collected in 198 of the total of 244 patients in this trial. Of those in the PF preservation group 31 out of 100 patients (31%) developed seroma, versus 39 out of 98 patients (39.8%) in the PF removal group. This difference was not statistically significant (p=0.20).14 Abdelhamid et al reported a significant reduction of the incidence of seroma in the PF preservation group (5.6% vs 24.3%, p=0.025).10 In the study by Salgarello et al three seromas were reported (1.3%).13 However, the definition of seroma was not provided in both studies. The report by Sandelin et al did not report on occurrence of seroma.16 Metastasis Mortality PF preservation PF removal P-value PF preservation PF removal P-value n=30 (24.0%) N=28 (23.0%) P=0.73 n=35 (28.0%) n=28 (23.0%) p=0.37 n= 39 (31.7%) n= 35 (28.9%) P=0.61 n=53 (43.1%) n=47 (38.8%) P=0.47 - - - - - - - - - N=31 (15.4%) - - - - - - - - 3

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