TABLE OF CONTENTS Chapter 1 | General introduction and thesis outline 7 Part I Oncoplastic breast surgery 15 Chapter 2 | An analysis of complication rates and the influence on patient satisfaction and cosmetic outcomes following oncoplastic breast surgery 17 Journal of Plastic, Reconstructive & Aesthetic Surgery, 2022 Part II Pectoral fascia preservation in immediate breast reconstruction 33 Chapter 3 | Pectoral fascia preservation in oncological mastectomy to reduce complications and improve reconstructions: a systematic review 35 Plastic Reconstructive Surgery Global Open, 2021 Chapter 4 | Preservation of the pectoral fascia in mastectomy with immediate reconstruction, a nationwide survey 53 Journal of Surgical Research, 2023 Part III Implant loss risk in implant-based breast reconstruction 63 Chapter 5 | Implant loss and associated risk factors following implantbased breast reconstructions 65 Plastic Reconstructive Surgery Global Open, 2021 Chapter 6 | Nation-wide validation of a multicenter risk model for implant loss following implant-based breast reconstruction 81 Journal of Plastic, Reconstructive & Aesthetic Surgery, 2022 Chapter 7 | Risk prediction of implant loss following implant-based breast reconstruction: a population-based study using Dutch Breast Implant Registry (DBIR) data 95 Submitted Discussion and Conclusion 115 Chapter 8 | General discussion and future directions 117 Chapter 9 | English summary / Nederlandse samenvatting 129 Appendix | List of publications / Dankwoord / Curriculum vitae 137
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