86 Chapter 6 Table 2. Baseline comparison between cohorts Baseline characteristics Validation cohort (n=3769) Multicenter cohort (n=297) P-value* Age, years 48.8 ± 11.3 47.5 ± 11.3 0.068 BMI, L2/m 24.7 ± 4.2 25.3 ± 4.8 0.033 Obesity 401 (10.6) 47 (15.8) 0.006 ASA score <0.001 I 1919 (51.3) 75 (25.3) II 1652 (44.2) 203 (68.4) III 169 (4.5) 18 (6.1) IV 0 (0) 1 (0.3) Missing 29 0 Current smoker 486 (12.9) 47 (16.2) 0.108 Missing 0 7 Indication <0.001 Breast cancer 3064 (81.3) 211 (71.0) Prophylactic 705 (18.7) 86 (29.0) Type reconstruction 0.453 Permanent implant 832 (22.1) 60 (20.2) Tissue expander 2937 (77.9) 237 (79.8) Nipple preserving 1126 (29.9) 119 (40.5) <0.001 Missing 0 3 Volume permanent implant 388 (295-480) 413 (305-515) 0.007 Volume tissue expander <0.001 <100 848 (30.2) 68 (28.8) 100-200 1677 (59.7) 114 (48.3) >200 285 (10.1) 54 (22.9) Missing 127 1 Baseline characteristics of the validation cohort compared to the baseline characteristics of the previous multicenter cohort.
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