106 Chapter 5 RESULTS Study population From the 8261 participants included in EUROASPIRE V, 43 were excluded due to a missing BP measurement. Altogether, 6547 (79.7%) patients fulfilled the definition of hypertension and were included in the main analysis. From these, 157 (2.4%) patients didn’t have a previous record of hypertension in their medical records or had been told they had raised blood pressure. More than one in four participants (27.1%) were female, mean age was 64.5 (sd 9.2) years, and 43.1% had tertiary educational level. Regarding cardiovascular risk factors, 15.1% of participants reported current smoking, 84.2% were obese or overweight, 71.6% presented with LDL levels ≥1.8mmol/L, and 45.0% were diabetic (Table 2). Awareness Eighty-nine percent of patients reported to have been informed by a health professional that they had raised blood pressure, 68.9% were aware of their BP target, and 87.4% of their latest BP measurement result. Overall hypertension awareness was achieved by 59.9% of patients (Table 3). As shown in Figure 1 and Table 3, 30.3% of patients were aware, treated and controlled, 28.0% were aware and treated but not controlled, and 8.0% were not aware, untreated and not controlled. Hypertension awareness was independently associated with female sex (odds ratio (OR) 1.27, 95% confidence interval (CI) 1.07-1.51), PTCA as index event (OR 1.37, 95%CI 1.091.73), secondary (OR 1.34, 95% CI 1.05-1.71) and tertiary education (OR 1.70, 95%CI 1.33-2.17), medication adherence (OR 2.26, 95%CI 1.81-2.82), using a higher number of antihypertensive medications (OR 1.24, 95%CI 1.17-1.31), conducting lifestyle changes (OR 1.59, 95%CI 1.36-1.86); and negatively associated with diabetes (OR 0.85, 95%CI 0.730.99) and current smoking (0.79, 0.65-0.97) (Table 4). Supplementary Table 1 shows the multivariable analysis results stratified by sex. Treatment Most patients defined as hypertensive in EUROASPIRE V were using at least one drug to lower blood pressure (91.1%), 85.7% reported to take their medications all the time or nearly all the time, and the mean number of antihypertensive medications was 2.7 (sd 1.4). Use of medication to lower blood pressure was independently associated with female sex (OR 2.03, 95%CI 1.56-2.63) and undertaking lifestyle changes (OR 1.26, 95%CI 1.02-1.56), and inversely associated with LDL ≥1.8mmol/L (OR 0.74, 95%CI 0.59-0.92). Hypertension control Hypertension control was attained by 46.4% (95% CI 45.2%- 47.6%) of participants. Mean BP level was 124 mmHg (SD 10.2 mmHg) among participants with controlled hypertension and 151 mmHg (SD 15.2 mmHg) in participants with uncontrolled hypertension (Table 2).
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