4. Effects of keloid properties on treatment efficacy 108 Table 1. Results of the included studies Abbreviations: BTX-A, Botulinum toxin type A; 5-FU, 5-flurouracil; duration, duration prior to treatment; IL, intralesional; No, number; NR, Not reported; NS, no significant correlation with treatment efficacy; POSAS, Patient and Observer Scar Scale; PRP, platelet rich plasma. TCA, triamcinolone acetonide; VAS, Visual Analogue Scale; VRS, Verbal Rating Scale; VSS, Vancouver Scar Scale; VTG, Verapamil treatment group SeragEldin et al, 2021 Duration, thickness A: IL TCA, B: IL pentoxifylline, C: IL TCA + IL pentoxifylline Duration and thickness: NS. VSS score Mean duration(months): 7.0 (n=10), 7.2 (n=10), 12.4 (n=10). Mean thickness (cm): 2.9(n=10), 4.4(n=10), 3.0 (n=10). Total no. keloid patients: 30. Tawfic et al., 2020 Duration, location A: Fractional CO2; B: Nd:YAG laser; C: CO2 + Nd:YAG lasers - Duration: significant negative correlation between keloid duration and treatment efficacy with Nd:YAG laser (NS for fractional CO2 laser or a combination of fractional CO2 laser followed by Nd:YAG laser). - Location: NS. VSS score Mean duration (years): 8.84 (n=30). Location: upper extremities (n=13), lower extremities (n=5), trunk (9), lower extremities + trunk (n=3). Total no. keloid patients: 30.
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