6. Needle-free electronically-controlled jet injector treatment with bleomycin and lidocaine is effective and welltolerated in patients with recalcitrant keloids. 164 Median (Q1– Q3) Median in difference p Value Vascularity 7 (5–8) −2 (−2 to 0) 0.159 Pigmentation 6 (4–8) 1 (0−1) 0.380 Thickness 6 (4–8) −2 (−2 to −1) 0.354 Relief 6 (5–8) −1 (−2 to 0) 0.081 Pliability 7 (5–8) −2 (−3 to −1) 0.002 Surface area 6 (4–8) −1 (−1 to 0) 0.070 Overall assessment 7 (5–8) −1 (−2 to −1) 0.019 Total POSAS observer scale 40 (29–51) −7 (−11 to −3) <0.001 Median (Q1–Q3) Median in differences p Value Pain 4 (2–5) −1 (−2 to 0) 0.144 Itching 7 (5–8) −2 (−3 to 0) 0.049 Color 8 (7–10) 0 (−2 to 1) 0.435 Stiffness 8 (6–8) −1 (−2 to 0) 0.006 Thickness 8 (7–9) −1 (−2 to 0) 0.023 Irregularity 8 (6–9) −1 (−2 to 0) 0.205 Overall opinion 8 (7–10) 0 (0–1) 0.054 Total POSAS patient scale 41 (37–47) −6 (−13 to −3) <0.001 Table 2. Clinical improvement assessment using POSAS. Abbreviation: POSAS, Patient and Observer Scar Assessment Scale. a One patient (n = 1) was missing due to the patient's pregnancy wish. b Median in differences is the median change of paired observations before and after treatment.
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