1. General introduction 20 Therefore, it is important to use adequate safety measures such as protective gloves, goggles, and a smoke evacuator or a FFP-2 mask to effectively capture these aerosols.62 Moreover, intralesional bleomycin administration harbors the risk of mild to moderate adverse effects, including necrosis and ulceration. To minimize the risk of superficial necrosis, it is important to avoid too superficial drug delivery, and target the reticular dermis using a standardized and consistent drug delivery technique. EPI could potentially facilitate a standardized, effective and safe drug delivery of bleomycin in keloidal scars.
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