1. General introduction 24 routinely asking about injection-related pain and side effects. Two retrospective cohort studies that evaluated the effectiveness, tolerability and patient satisfaction in patients in a real-world setting were performed. Since patients with recalcitrant keloids have been treated successfully and safe according to the BLEOJET study, hereafter adult patients from the outpatient clinic of Erasmus MC with recalcitrant keloids were offered treatment with a combination of bleomycin and lidocaine according to regular care. Lidocaine was added to the bleomycin in a real-world setting, because according to the data from the BLEOJET study, EPI-assisted injections with bleomycin monotherapy still resulted in relatively high injection-related pain, although assessed as less painful than needle-assisted injections. Patient reported outcome measures including the Patient and Observer Assessment Scale (POSAS) were used to assess effectiveness.
RkJQdWJsaXNoZXIy MTk4NDMw