2. Efficacy and safety of needle free jet injector assisted intralesional treatments in dermatology—a systematic review. 41 2. 2. RESULTS Our literature search identified 1326 records. Duplicates were removed. Based on title and abstract, 985 articles were screened. Full texts of 71 articles were assessed for eligibility of which 37 studies were selected with a total of 1911 participants (Fig. 1). The included studies comprised 6 RCTs, 6 CCTs, 16 prospective cohorts, 5 retrospective cohorts, and 4 case series. The studies investigated needle-free jet injector-assisted intralesional treatments for atrophic and hypertrophic scars, keloids, alopecia areata, hyperhidrosis, nail diseases (psoriasis, lichen planus, and idiopathic onycholysis), nonmelanoma skin cancer (basal cell carcinoma (BCC), squamous cell carcinoma (SCC), Bowen’s disease, and Paget’s disease), common warts, granuloma annulare, lichen simplex chronicus, psoriasis, seborrheic dermatitis, aesthetic indications (wrinkles, rejuvenation, rhytides, facelift), and local anesthesia. Figure 1. Study flow diagram of exclusion process resulting in 37 included studies
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