112 Chapter 3 Table 3. Detailed information about the supporting evidence for the recommendations Guideline Diagnostic accuracy Burden of the test Natural course Treatment effectiveness Considered Link between test result and administration of treatment Considered Considered with systematic review of the literature Considered with systematic review of the literature and certainty in the evidence Considered Considered with systematic review of the literature Considered with systematic review of the literature and certainty in the evidence Considered Considered with systematic review of the literature Considered with systematic review of the literature and certainty in the evidence Considered Considered with systematic review of the literature Considered with systematic review of the literature and certainty in the evidence CRP DGPB, 2016 [20] + - - - - - - - - - - - - ACP, 2019 [21] + + + - - - - - - - - - - MoPH, 2019 [19] - - - - - - + - - + - - - DGPI, 2017 [22] + - - - - - - - - - - - - Colonoscopy ESMO, 2020 [25] - - - - - - - - - + - - - AWMF, 2019 [23] - - - - - - - - - - - - - ACPGBI, 2017 [26] + - - - - - - - - - - - - FMS, 2019 [24] + - - + - - - - - - - - - NHG, 2017 [27] + - - + - - - - - - - - - FeNO AWMF, 2020 [28] + + + - - - - - - + + + - MoPH_A, 2019 [31] - - - - - - - - - - - - MoPH_C, 2019 [33] - - - - - - - - - - - - - NAEPP, 2020 [29] + + + + - - - - - - - - - NICE, 2020 [30]† + + + - - - - - - - - - - SIGN, 2019 [32] + - - - - - + - - - - - - +: yes; +/-: unclear; -: no; †This CPG contains two separate recommendations concerning the use of FeNO in the diagnosis of childhood respectively adult onset asthma; the scores are identical
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