142 Chapter 4 developers responsible for developing recommendations about healthcare related testing seems necessary. Guidelines are typically developed by panels (also called guideline development groups), consisting of experts from different backgrounds and perspectives: (1) healthcare professionals, such as doctors and nurses, with expertise on the topic of interest, (2) healthcare consumers, such as patients, with experience in the topic of interest, (3) methodologists with specific expertise on guideline methodology and (4) chairs leading the guideline panel. Our study aimed to define the knowledge required for healthcare professionals and consumers in guideline panels (further referred to as guideline panel members) to adequately contribute to the development of guideline recommendations about healthcare related testing. The results of this study can inform specific training programs for guideline panel members involved in developing healthcare related testing recommendations. Methods Design This was a developmental study with a multi-staged approach. We set up a project team (MKT, JSB, TvdW, MWL) to conduct the study. Based on an exploratory literature review, the project team drafted a first set of minimum knowledge components, and then conducted qualitative semi-structured interviews with experts to reflect and to comment on the set. Then, the refined final set of knowledge components was approved by the interviewees. This study was conducted between January 2022 and September 2023. Literature review The aim of the literature review was to collect potentially relevant knowledge components from existing literature. The first author of this study (MKT) systematically searched the literature, focusing on knowledge needed for guideline development and evidence-based medicine using Medline on January 7th, 2022, using the following search string: ((((((("Evidence-Based Medicine"[Majr]) OR ("Evidence-Based Practice"[Majr])) OR (evidence based[Title])) OR ("Guidelines as Topic"[Majr])) OR (protocol*[Title])) OR (recommendation*[Title])) OR (guideline*[Title])) AND ((((((knowledge*[Title]) OR (competenc*[Title])) OR ("Knowledge"[Majr])) OR ("Health Knowledge, Attitudes, Practice"[Majr])) OR ("Professional Competence"[Majr])) OR ("Clinical Competence"[Majr])) with filters for studies published in the last 10 years, and studies published in English, Dutch or German language.
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