48 Chapter 2 97 96 (351) 98 limit 97 to yr="1998 -Current" (312) 99 *rhinitis, allergic/ or *rhinitis, allergic, perennial/ or *rhinitis, allergic, seasonal/ (16022) 100 (rhinitis adj3 (allerg* or perennial or nonseasonal or season*)).ti. (8398) 101 ((hay adj fever) or pollinosis or nasal allerg* or nose allerg*).ti. (2570) 102 3 or 5 or 99 or 100 or 101 (18433) 103 92 and 102 (173) 104 95 and 102 (428) 105 98 and 102 (182) 106 (prognos$ or outcome$ or follow-up or predict$).tw,sh. (3682599) 107 exp Prognosis/ (1475607) 108 Disease Progression/ (144837) 109 ((clinical or natural$ or disease$) adj (progress$ or course$ or histor$)).tw,sh. (221264) 110 Time Factors/ (1140587) 111 106 or 107 or 108 or 109 or 110 (5219716) 112 exp Cohort Studies/ (1812919) 113 (cohort$ or compar$ or longitudinal$ or prospective$ or multivariate or reproducib$).tw,sh. (6934341) 114 112 or 113 (7498020) 115 111 and 114 (2626014) 116 6 and 26 and 115 (3473) 117 116 (3473) 118 limit 117 to yr="1998 -Current" (2979) 119 118 and 102 (1903) 120 119 and 45 (213) 121 (prognos$ or outcome$ or follow-up or predict$).ti. (754298) 122 exp *Prognosis/ (37741) 123 *Disease Progression/ (6228) 124 ((clinical or natural$ or disease$) adj (progress$ or course$ or histor$)).ti. (29727) 125 *Time Factors/ (2184) 126 121 or 122 or 123 or 124 or 125 (808389) 127 114 and 126 (515383) 128 119 and 127 (198) 129 128 (198) Embase search – 11 January 2019 1 allergic rhinitis/ or perennial rhinitis/ or pollen allergy/ (36718) 2 (rhinitis adj3 (allerg* or perennial or nonseasonal or season*)).tw. (26427) 3 (rhinitis adj3 (allerg* or perennial or nonseasonal or season*)).kw. (6196) 4 ((hay adj fever) or pollinosis or nasal allerg* or nose allerg*).tw. (7178) 5 ((hay adj fever) or pollinosis or nasal allerg* or nose allerg*).kw. (1309) 6 or/1-5 (45786) 7 pollen/ or grass pollen/ (19487) 8 mite/ (9977) 9 exp pyroglyphidae/ (10784) 10 exp fungus/ (459268) 11 (aero?allergen? or pollen or mite? or mould? or mold? or fungi or cat? or dog? or (animal adj dander)).tw. (487040) 12 (aero?allergen? or pollen or mite? or mould? or mold? or fungi or cat? or dog? or (animal adj dander)).kw. (55047) 13 or/7-12 (887249) 14 immunoglobulin E/ (75528) 15 ((IgE or sIgE or (immunoglobulin? adj E)) adj3 (test* or analys* or diagn* or measur* or level?)).tw. (25978) 16 ((IgE or sIgE or (immunoglobulin? adj E)) adj3 (test* or analys* or diagn* or measur* or level?)).kw. (178) 17 exp hypersensitivity/di (52556)
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