Chapter 4 166 Table S4. Continued Gene logFC Average Expression CCL4 1.37652182502365 -1.15162060939353 CD244 1.0140109917243 -4.13601859978355 GIMAP4 0.910008059694032 -0.110032084999837 CCL5 1.34205185377604 -0.41616328442252 IL6 1.6751565235166 -1.85138061368234 CXCL14 -2.43479633694284 1.19030995683133 TNFRSF1B 0.931778521160674 -0.633533347850366 IL2RB 1.20344276687788 -1.41007205577328 CD40 0.917900814704211 -0.693642929932606 IFIT2 1.18990439064898 -1.60118350410009 SLAMF7 1.310766818109 -2.38257048577135 HLA-F 1.05618112032267 -0.105931695806803 NCR1 0.960005951631412 -4.16203875925747 CD7 1.15797115824849 -2.92732873037538 HLA-C 0.943096476582807 3.12629587925205 HSD11B1 1.23825740268296 -2.96366472328225 OAS1 0.916330131374769 0.7835427792938 OAS2 0.964878990316807 0.159982062948577 PIK3CD 0.910004000640195 -1.47076303939425 RRM2 0.861345905307591 -0.16258390339206 Table S5. Predictive accuracy of PDCD1 gene expression signature, summary of training and validation results. Biomarker AUC Cut-off Training cohort (n=58) PDCD1 0.71 95% CI: 0.54-0.88 <0.20 vs ≥0.20 Validation cohort (n=42) PDCD1 0.74 95% CI: 0.50-0.99 <0.20 vs ≥0.20
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