Karlijn Hummelink

Chapter 5 206 9. Kaplan-Meier plots of OS and PFS by test classification for the subgroup of validation set 1 treated with CPIs in third or higher line Supplementary Figure 7: Kaplan-Meier plots of OS and PFS by test classification for patients in validation set 1 treated with CPIs in third or higher lines. 10. Association of PD-L1 status with test classification in the pooled analysis of second line patients Supplementary Table 19: PD-L1 status by test classification (pooled second line patients) Resistant (n=96) Intermediate (n=80) Sensitive (n=73) PD-L1 Positive (≥1%) 21 (22) 20 (25) 16 (22) PD-L1 Negative (< 1%) 25 (26) 28 (35) 16 (22) NA 50 (52) 32 (40) 41 (56) NA, not available

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